Humans with stripes1/17/2024 I think the idea that they were visible under UV may be associated with those visualizations (where they appear to fluoresce green), whatever his source material. calls them "stripes" and provides a diagram, then notes that you can't actually see them with your naked eye. Genetic female mammals specifically are understood to have a limited degree of epigenetic chimerism mosaicism in the expression of X-chromosome metabolic products. I suspect CSI’s dramatization of this turned it into a generalization because the early the articles popped up around that time. So basically a small subset of humans with specific genetic conditions have lines of Blaschko and small portion of these lines are best visualized under UV light. I will have to ask my dermatology colleagues, but my best guess is this is going to end up being a common misconception.Įdit: Also found mention of a CSI episode (transcript: ) in 2004 where apparently a chimeric patient was discovered using UV light showing lines of Blaschko. This article ( ) is an open access review of skin patterns that specifically discuss Blaschko's lines and don't mention UV light at all. Moreover, I could not find any primary source from these articles other than links to youtube videos, blog posts, or each other. On a quick google search, I see a number of articles implying humans have Blaschko lines that can be visualized under UV light, but this is quite misleading because lines of Blaschko are only present when cells of multiple lineages are present (mosiacism or chimerism) and, while UV light can help ID the subtle cases, are clearly visible to the naked eye most of the time. I don't have direct expertise on this topic, but I am part of a clinic that sees patients with genetic skin conditions and the answers in this thread about lines of Blaschko surprised me. We make our world significant by the courage of our questions and by the depth of our answers.
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